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Seitentitel
Supergenics
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Seitenbeschreibung
Supergenics specializes in stem cell therapies, exosomes, and regenerative medicine. Learn about our innovative treatments!
Länge : 123
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Eigenschaft
Inhalt
type
website
url
https://www.supergenic.com.my/
title
Supergenics
description
Supergenics specializes in stem cell therapies, exosomes, and regenerative medicine. Learn about our innovative treatments!
image
/assets/img/sg_meta_1200x630.webp
image:width
1200
image:height
630
image:alt
Supergenics Berhad company Logo
site_name
Supergenics
locale
en_US
locale:alternate
zh_CN
Überschriften
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[H1] Supergenics
[H1] Supergenics Berhad
[H2] Company No. 201601043153(1214095-X)
[H4] WHAT IS ISO/IEC 17025 ?
[H4] MEASUREMENT UNCERTAINTY
[H4] UNCERTAINTY SOURCE
[H4] TRACEABILITY
[H4] SUPERGENICS ACCREDITATIONS
[H4] Services of Beautifully Built :
[H4] BIOLOGY SERVICES OFFERED :
[H4] Service Offered of Biology Mechanical :
[H4] OVERVIEW OF Calibration Services :
[H4] Our Testing Services Include :
[H4] Introduction to Stem Cells
[H4] Classification of Stem Cells
[H4] about mesenchymal stem cells (MSC)
[H4] Why Wharton's Jelly
[H4] Obtaining Mesenchymal Stem Cells
[H4] Characteristics of Stem Cells
[H4] What is Mesenchymal stem cell MSC
[H4] Where does Mesenchymal stem cell MSC come from?
[H4] Wharton's Jelly umbilical cord tissue, the main source of our MSC
[H4] The multilineage differentiations allow MSC to become
[H4] The main causes of aging:
[H4] How does Stem Cell works?
[H4] What is NK cell ?
[H4] What NK cells does ?
[H4] Are we 'immortal' or 'vulnerable'?
[H4] A reduced in NK cell activity
[H4] Quick-Fix Solution: NK Immunotherapy
[H4] How NK cells targeted on cancerous cell
[H4] How NK cells targeted on virus infected
cell
[H4] WHAT ARE EXOSOMES ?
[H4] NUMBER OF EXOSOME PUBLICATIONS
[H4] CLINICAL TRIALS OF EXOSOME
[H4] BENEFITS OF USING EXOSOMES
[H4] WHY WE USE EXOSOMES
[H4] POTENTIAL USE OF EXOSOMES
[H4] APPLICATIONS OF EXOSOMES – COSMETIC USES
[H4] APPLICATIONS OF EXOSOMES – THERAPEUTIC USES
[H4] Mesenchymal Stem Cell derived exosomes
[H4] Chronic Wounds
[H4] How MSC Exosomes help in traumatic wound healing
[H4] How MSC Exosomes help in diabetic wound
healing
[H4] What is Ischemic Heart Disease
[H4] How MSC Exosomes help in ischemic heart
diseases
[H4] Why are exosomes ideal for use in
therapy?
[H4] Safety Evaluation
[H4] Safety Evaluation
[H4] Aging
[H4] Regenerate New Blood Vessel
[H4] Regenerate New Blood Vessel
[H4] Stemness Marker
[H4] Therapeutic Potential
[H4] Osteogenic Differentiation
[H4] Safety Evaluation
[H4] Safety Evaluation
[H4] Aging
[H4] Regenerate New Blood Vessel
[H4] Regenerate New Blood Vessel
[H4] Stemness Marker
[H4] Therapeutic Potential
[H4] Osteogenic Differentiation
[H4] International Standards
[H4] International Publications
[H4] Cited
[H4] Years of Experience
[H4] NPRA National PharmaceuticalRegulatory Agency
[H4] NPRA National PharmaceuticalRegulatory Agency
[H4] AABB Association forthe Advancement ofBlood and Biotherapies
[H4] Mission
[H4] Philosophy
[H4] Commitment
[H4] 2020, The First Company Listed on BURSA Malaysia
[H4] Advanced Licensed EU GMP Stem Cell Production Plant PIC/S CGTP cGMP
[H4] Cell Therapy Expertise
[H4] ISO/IEC Certification, ILAC Standards Malaysia
[H4] Contact Us:
[H4] Email:
[H4] Location:
[H4] Opening-Hours:
[H5] ISO/IEC 17025 is an international standard that sets out the general requirements for the competence, impartiality, and consistent operation of laboratories performing testing and calibration activities. It is applicable to all types of laboratories, including those in the public and private sectors, regardless of their size or field of testing or bration. It is used as a tool to assess and demonstrate the technical competence and reliability of laboratories.
[H5]
Over the years, ISO/IEC 17025, General requirements for the competence of testing and calibration laboratories, has become the international reference for testing and calibration laboratories wanting to demonstrate their capacity to deliver trusted results. The International Standard, published jointly by ISO and IEC International Electrotechnical Commission, contains a set of requirements enabling laboratories to improve their ability to produce consistently valid results.
[H5]
• In the international ISO standards, Measurement Uncertainty MU holds significant importance
• Mathematical precision in addressing both statistical and systematic errors
• Crucial in ISO standards to ensure reliable and comparable measurement results
• Enhances the trustworthiness and consistency of measurement data worldwide
[H5]
[H5]
[H5]
Technical Requirements
Our Supergenics lab is equipped with qualified and competent personnel which have undergone appropriate training to accomplish their testing and calibration tasks
Management System
Our laboratories maintain an organised management system with documented procedures and quality policies to manage the quality of our findings effectively
Impartiality
We demonstrate impartiality and do not allow any conflicts of interest such as commercial, financial or other pressuring factors that could compromise the quality or integrity of our services
Reporting
We provide clear and accurate test or calibration results, including uncertainty of measurement when relevant, to our clients
[H5]
Supergenics has achieved ISO/IEC 17025:2017 accreditation for Testing and Calibration Laboratories, including Mesenchymal Stem Cell Count and Viability. Additionally, they have received approval for four scopes from Standard Malaysia: Cell Count and Viability, Gram Stain, and Trilineage Differentiation and Characterization Assay. Their commitment to providing cost-effective, efficient, reliable, and high-quality solutions and services to customers is evident.
Supergenics, as a trusted partner, ensures optimal product performance through meticulous maintenance services, underscored by prestigious ISO/IEC 17025 certification from both ILAC and the Department of Standards Malaysia JSM in testing. Within their testing services, Supergenics excels in precise calibration of Temperature Sensors, RH Sensors, Airflow sensors, and Pressure Sensors, guaranteeing accuracy and efficiency crucial for various applications.
The ISO/IEC 17025 accreditation from JSM signifies Supergenics' adherence to global standards, ensuring services of the highest quality and reliability. Their comprehensive offerings include functional testing, traceable calibration to SI units, and detailed calibration certificates. By choosing Supergenics, customers align their equipment with internationally recognized standards, backed by SAMM accreditation with ILAC Mark for precision and quality assurance.
[H5] ISO/IEC 17025 Accredited Calibration for Temperature Sensors
ISO/IEC 17025 Accredited Calibration for Relative Humidity Sensors
Calibration for Airflow Devices
Calibration for Differential Pressure Sensors
ISO/IEC 17025 Accredited Testing for Controlled Environment Air Temperature
ISO/IEC 17025 Accredited Testing for Controlled Environment Relative Humidity
Testing for Controlled Environment Airflow
Testing for Controlled Environment Differential Pressure
[H5] Comprehensive Stem Cell Characterization
Stem Cell for Research, Preclinical and Clinical Applications
[H5] Comprehensive Stem CellCharacterization
Stem Cell for Research, Preclinical and Clinical applications
Calibration: Temperature and relative humidity meters
Testing: Air temperature and relative humidity for controlled environment
[H5] Functional testing
Calibration traceable toNational Metrology Institute
Calibration certificate with as-found and as-left results
Measurement report with 95% confident level Measurement Uncertainty
Provide with correction factor for accurate measurement
[H5] Measurement results traceable to National Metrology Institute
Real time measurement related to the controlled environment
Service report with unambiguous data and information
[H5] Stem cells are undifferentiated cells which have the ability to differentiate into
specialised cells with specialised functions. They have the remarkable property of
dividing infinitely to replace worn out cells after death. With each division, the
new cell has the potential to remain as a stem cell, or to specialise into a cell
type, such as blood cells, skin cells and brain cells.
[H5] Stem cells have different potencies, which refers to the ability of a stem cell to
differentiate into more specialised cell types. Cells with greater potency can
differentiate into a wider variety of cell types as compared to cells with lower
potency. The classifications are as follows: totipotent stem cells, pluripotent stem
cells and multipotent stem cells. Totipotent stem cells can give rise to any of the
220 different cell types in the human body, as well as form embryonic stem cells.
Pluripotent stem cells can differentiate into any cell type, but don't have the
ability to form embryonic stem cells. Multipotent stem cells can develop into a
limited number of cell types in a particular lineage, which include ectodermal,
endodermal and mesodermal cells.
[H5] MSC is a type of multipotent stem cell that has the ability to self-renew and to
differentiate into a limited number of cell types. The sources of MSC are from the
bone marrow, umbilical cord, adipose tissue, dental pulp and peripheral blood.
[H5] Wharton's jelly is the main connective tissue found within the umbilical cord and is
rich in MSCs, in most instances, mesenchymal stem cells are typically derived from
bone marrow tissue using a painful and invasive process for extraction. Wharton’s
jelly MSCs are far easier and less invasive to retrieve, and come with many other
benefits compared to using MSCs derived from other sources. MSCs are also found in
more abundant numbers in Wharton’s jelly compared to other sources, and the cells
harvested are younger hence more viable. Aside from its powerful immunomodulatory
effects and potent anti-inflammatory effects, it is also able to stimulate
angiogenesis, the formation of new blood vessels, as well as having an increased
proliferative capacity.
[H5] A process called cell culture is used to grow mesenchymal stem cells under a
controlled environment. The umbilical cord is first collected and disinfected, it
needs to be incubated and given constant medium changes. Supergenics has developed a
new innovative method to further increase the propagation of cells reaching abundant
numbers, increasing the efficiency of our lab work. The newly grown cells are then
cultured and cryogenically stored, and can be implanted into patients when needed.
[H5] MSCs have several characteristics including low immunogenic properties,
immunosuppression and the ability to exhibit the paracrine effect. MSCs secrete
growth factors and chemokines, which can stimulate angiogenesis and to reorganise
the extracellular matrix in scar areas.
The paracrine effect is a mechanism that allows specialised donor cells to stimulate
the patient's cells to repair diseased tissue, without donor cells directly
contributing to the new tissue. Donor cells, MSCs, are attracted to the cytokines
secreted by damaged cells, and can help to reduce inflammation, promote cell
proliferation and increase vascularisation and blood flow in areas that need to be
healed.
[H5] MSC is a type of adult multipotent stem cell that exhibit the special characteristics of self-renewal and multilineage differentiation.
[H5] MSC are found to be original from umbilical cord, bone marrow, adipose tissues, dental pulp and peripheral blood. In our lab, the MSC will be taken from Wharton's Jelly which pose great potential in differentiation stage of cell.
Liver and Lung
Placental
tissue
Synovial
membrane
Dental Pulp
Bone marrow
Endometrium
Umbilical cord blood
or tissue (Whartons Jelly)
Amniotic fluid
Mesenchymal
Stem Cell
Adipose tissue
[H5] Wharton's Jelly is rich of mesenchymal stem cell tissue that is widely applied in treating different kind of diseases or conditions as well as regenerating into most of the types of cells actively. MSC derived from Wharton's jelly are the stem cell with strong capacity and readily to differentiate into the required cell type.
[H5] These cells can become different cell types within the mesodermal lineage, which includes a wide range of cell types found in connective tissues, bone, cartilage, and adipose tissue.MSC are considered multipotent, meaning they have the potential to differentiate into several.
Cardiomyocytes
Respiratory Cells
Renal Tubule
Osteocytes
Epithelial Cells
Adipocytes
Enterocytes
Neuron
Myocytes / Tenocytes
Chondrocytes
Hepatocytes
[H5] Endothelial aging
Age increased > endothelial wall stiffens > more fats deposition > narrowing lumen of blood vessel > hight risk of sub-chronic health conditions
YOUNG
ELDERLY
Mitochondria dysfunctions
Age increased > lack of mitochondria > less energy ATP generated > lack of powerhouse > cellular processes disrupted > diseases developed
[H5] Mechanism of actions, how does MSC helps to repair damaged cells?
Angiogenesis
Due to endothelial aging, our blood vessels have become rather fragile and stiffen. Consequently, our body blood circulation will be affected as well as metabolism rates. Under this scenario, the angiogenic property of stem cell not just only helps to repair the blood vessel, it further regenerates new blood vessel. Therefore, the function of our blood circulation system will be restored.
Mitochondria
Mitochondria is a double-membrane bound organelle that plays important role in energy generation through aerobic respiration. Adenosine triphosphate ATP as the form of generated energy is essential to carry out cellular biochemical reactions.
Mitochondria Transfer
MSC acts accordingly to homing effects in which the damaged, aging cells will release signal to be captured by MSC. Continuously, MITOCHONDRIA TRANSFER will be carried out to replenish the powerplant of aging cells. This allows aging cells and tissues to regain their functions.
TNT
Donor
Recipient
Dendrite
Donor
Recipient
Extrusion and Internalization
Donor
Recipient
Microvesicle
Donor
Recipient
[H5] Natural killer NK cells are a group of innate white blood cell with cytolytic
activity against virus-infected cells and physiologically stressed cells like tumor
cells. It acts as the frontliner of our immune system to approach the abnormal cells
at first. About 10 - 15% of peripheral blood mononuclear cells
PBMC are consist of this NK cell.
[H5] The name 'natural killer' derived from the ability of NK cells that target abnormal
cells without the need for prior activations due to the absence of specific cell
surface receptors on it.
NK cells able to detect the cytokines released by pathogen-infected cells or malignantly transformed cell
This in turn will bind to the activating ligand of NK cells
Once NK cells activated, cell-mediated cytotoxicity begin
By producing chemokines and cytokines against the abnormal cells
Modulating the functions of other immune cells
Eventually, lead to the lysis of infected cells and malignant cell
Natu
r
al
Killer Cell
Natu
r
al
Killer Cell
Normal Cell
Abnormal cell lacking
MHC class 1 molecules
Kill
No
A
ttack
MHC class 1
molecule
Perforin and
granzymes
Killer-inhibitory
receptor
Killer-activating
receptor
Ubiquitous
molecule
This characteristic of NK cells allows it to be widely applied in various
therapies including immunotherapy to fight against cancer and certain viral
diseases.
[H5] Are these sign and symptoms sound familiar to you?
• Delayed wound healing
• Chronic fatigue: Feels tired even after sufficient hours of sleep
• Digestive issues: constipations, diarrhea, bloating
• Frequent/Recurrent infection: sinus, UTI, ear infections or usually lungs or viral infections
• Aging
• Highly stressed
• Sedentary lifestyle
• Heavy smokers, Alcoholic
• Long-term exposed to harmful environment pollutions/hormones
• Family history of cancer
• Cancer patients or recurrence
[H5] • Cancers
Gastric cancer, breast cancer, prostate cancer, pancreatic cancer, colorectal
cancer, lung cancer, liver cancer, ovarian cancer, uterine cervical cancer, blood cancer, etc.
• Aging and contagious diseases
Herpes zoster, Alzheimer's senile diseases, human papilloma virus HPV
infection, AIDS HIV infection, chronic hepatitis, etc.
• Autoimmune Diseases
Diabetes, rheumatoid arthritis, inflammatory bowel disease IBD,
systematic lupus erythematosus Lupus, multiple sclerosis, etc.
• Other Stress, chronic fatigue, anti-aging, etc.
[H5] A promising anti-cancer strategy which flexible to be combined with other
conventional cancer therapies such as chemotherapy, radiotherapy, and surgery.
NK Immunotherapy enriches and enhances your own defend system against the enemies.
30-50 ml of Blood
QC Check With cGMP
Audited Facilities
Cell Expansion
and Activation
Autologous Transfer
• Autologous infusion, very low risk of rejection
• Expand the number, activate, and enrich the NK cells
• NK cells do not require genetically engineered
• Specifically targeted on malignant transform cell and virus infected cell only, greatly minimizing side effects
• An immunity booster, prevent infections, prevent cancers
[H5] NK cells target cancerous cells by recognizing the absence of MHC class I molecules
and the presence of stress-induced ligands or antibodies bound to the cancer cell's
surface.
Sources:
https://blog.codondex.com/2019/09/hope-for-p53-autologous-natural-killer.html
[H5] A series of microscopic picture on HIV-1-infected cell killing by NK cells. These
pictures were taken every 5 minutes and lead to the dying of cells.
Source:
https://research.pasteur.fr/en/team/virus-and-immunity/
Green:
HIV-1 infected cell
Blue dye:
Dying cell
Round, arrow pointed:
NK cell
Green: HIV-1 infected cell
Blue dye: Dying cell
Round, arrow pointed: NK cell
[H5] Exosomes are extracellular vesicles that contain nucleic acids, proteins, lipids and metabolites.
They are secreted by cells into the extracellular space where they undergo intercellular communication.
[H5] Exosomes, once thought to be just a waste product of cells, is growing rapidly in the industry as one of the most revolutionary discoveries of our time. It has many remarkable properties that allow it to perform various new therapies that have never been previously done.
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Exosome Publications
[H5] Throughout the years, exosomes derived from human, animal and plants have been extensively studied. As of 2023, there are currently 191 clinical trials being conducted on the study of exosomes.
Diagnostic Biomar
k
ers
Analysis
21.4%
13.9%
Cosmetic Study
3.0%
The
r
apeutic Study
61.7%
All data was obtained from clinicaltrials.gov
[H5] 1. Anti-inflammatory effects
• Secrete anti-inflammatory proteins, which promotes cell migration and proliferation to accelerate wound healing
2. Stimulate collagen synthesis
• Contain growth factors and microRNAs activate fibroblasts
• Fibroblasts are a type of cell that secretes collagen proteins for tissue repair
• Improve skin firmness and increased elasticity, reducing the appearance of wrinkles
[H5] 1. EXOSOMES ARE NON IMMUNOGENIC
• Will not trigger an immune response upon entry to the body
• Lack of immunogenic surface proteins
• Small size, less prone to immune recognition
• Carry immunosuppressive cargo microRNAs and regulatory proteins
2. Cell-to-cell communication
• Deliver signaling molecules to and from specific cells
3. Targeted delivery
• Travel to damaged cells to transfer necessary molecules in areas it is neede
• Repairing damaged skin cells and treating wounds
• Used in drug delivery
4. Can be stored
• Suitable for long term storage
• Effectiveness of exosome is unaffected
5. Stability
• Very stable substance
6. Non invasive sampling
• Can be isolated from various bodily fluids such as saliva, blood, urine and cerebrospinal fluid, culture medium
• Easy to obtain
[H5] 1. Diagnostic Biomarkers
• Act as early stage disease diagnostic tools
• Exosomes carry specific protein biomarkers specific to the disease
2. Immunotherapy
• Targeted antigen and drug carriers
• Can influence immune-regulation functions of target cells
• Potential cancer vaccines
3. Treatment against diseases
• Researchers are looking into potentially using exosomes to treat cardiovascular diseases, autoimmune diseases, and neurodegenerative diseases such as Alzheimers and Parkinsons
[H5] 1. Anti-Aging
• Increased collagen and elastin in human skin 3 days after treatment
2. Reduce Ultraviolet damage
• Cytokines, nucleic acids, proteins, and other bioactive compounds protect skin and reduce appearance of dark spot
• Proteins and lipids plump and hydrate skin, improving skin texture
3. Minimize Scarring
• Inhibit tissue over-proliferation, which causes scarring
• Improve skin hydration and elasticity, and reduce inflammation
[H5] 1. Reconstruction of skin flaps
• Promote angiogenesis and wound healing
• Increase survival rate of flap, decrease scarring
• Potential for skin regeneration: increased collagen and elastin
2. Early disease detection
• Exosomes carry disease-specific markers, can be used to detect diseases in early stages
• Cancer, inflammatory diseases, infections
3. Treating Wounds
• Stimulate cell proliferation, angiogenesis and stimulate collagen deposition
• Accelerate traumatic wound healing and chronic wound healing
[H5] Mesenchymal stem cells are multipotent stem cells that can differentiate into different cell types such as bone cells osteoblasts, cartilage cells (chondrocytes), muscle cells myocytes and more
[H5] A wound that does not heal in an orderly, timely sequence of repair, and the repair process fails to restore anatomic and functional repair after 3 months
[H5] 1. Cell Proliferation
• Cell Proliferation: The process where a cell grows and divides to form two daughter cells
• Exosomes contain growth factors that promote cell proliferation of fibroblasts and endothelial cells
2. Angiogenesis
• Exosomes use cell to cell communication to regulate gene expression in cells around the wound, promoting angiogenesis - the formation of new blood vessels. With increased blood flow to the wound site, a higher concentration of oxygen and nutrients are delivered to the wound, further speeding up the process of healing
3. Stimulate collagen deposition
• Exosomes contain growth factors and signaling molecules which stimulate fibroblast proliferation and induces the production of large amounts of collagen fibers
• Exosomes stimulate the differentiation of fibroblasts into myofibroblasts, which produces the extracellular matrix needed to restore tissue integrity
[H5] 1. Endothelial cells ECs
• Exosomes promote the function recovery of ECs
• Exosomes promote angiogenic response of ECs, forming more blood vessels hence improving wound closure
2. Fibroblasts
• In diabetes, fibrocytes are dysfunctional and have diminished proliferative capacity
• Exosomes promote the proliferation and migration of fibroblasts towards the wound
3. Macrophages
• M1 macrophages convert to M2 macrophages to guide the healing process to completion. However in diabetes, the conversion process is disrupted leading to prolonged inflammation
• Exosomes can facilitate the phenotypic polarisation of macrophages from M1 to M2, inhibiting inflammation and upregulating the expression of anti-inflammatory proteins, increasing wound healing rate
[H5] Ischemic Heart Disease: the weakening of the heart due to reduced blood flow, depriving the heart of oxygen
CAUSES OF ISCHEMIC HEART DISEASE:
• Atherosclerosis: buildup of plaque on the inner lining of arteries
• Blood clot
• Constriction of blood vessel
Narrowing of blood vessel restricts blood flow and heart muscles won't be able to receive oxygen, leading to its death-causing a myocardial infarction heart attack
[H5] 1. Stimulating angiogenesis
• Mesenchymal stem cell MSC derived exosomes deliver microRNAs to endothelial cells to increase angiogenesis
• Allows more oxygen to reach the heart
2. Paracrine signalling mediators
• Exosomes are released by MSCs and travel to target cells where it releases its cell contents into it. This helps to reduce inflammation, promote cell proliferation and increase vascularization and thus blood flow in damaged areas that need healing
3. Reduce scarring and fibrosis
• Fibrosis: The thickening and scarring of connective tissue
• Exosomes deliver cytokines and growth factors that stimulate the production of collagen and elastin
4. Prevent cardiomyocyte apoptosis
• Cardiomyocytes are cells found throughout the heart responsible for its contraction
• Prevents programmed cell death apoptosis of cardiomyocytes in oxygen-deprived conditions
• Helps preserve heart tissue
5. Immunomodulation
• Reduce inflammation and excessive immune activation
• More stable environment for repair of cardiomyocytes
6. Cardiac dilation
• Increases blood flow to heart, hence increasing oxygen flow
• Prevents further heart damage from hypoxic conditions
[H5] 1. Long term storage, off the shelf availability
• Keep chill for immediate use
• Under certain circumstances, it can be stored for up to 12 months
2. Reduced immunogenicity
• Lower risk of immune rejection
3. Reduced cell aggregation
• Cells have the potential to clump aggregate
together, leading to
microvascular occlusion
• No risk for exosomes due to small size
4. Targeted delivery
• Can be engineered to display specific surface proteins/ carry specific cargo
to target tumors to kill
5. Compatible with other treatments
• Can be used alongside chemotherapy or radiation therapy
6. Distributed homogeneously
• Distributed more evenly throughout target tissue
• Can reach areas that are hard for MSCs to reach due to their larger size
[H5] The biosafety evaluation of culture-expanded human chondrocytes with growth factor cocktail: a preclinical study
[H5] In situ normoxia enhances survival and proliferation rate of human
adipose tissue-derived stromal cells without increasing the risk of tumorigenesis
[H5] Pro-angiogenic potential of human chorion-derived stem cells in vitro and in vivo evaluation
[H5] Endogenous and induced angiogenic characteristics of human chorion-derived stem cells
[H5] Comparative profiling of stemness markers expressed by human umbilical
vein endothelial cells and human umbilical cord matrix-derived stem cells
[H5] Human adipose-derived mesenchymal stem cells promote recovery of injured
HepG2 cell line and show sign of early hepatogenic differentiation
[H5] Polycaprolactone-based scaffolds facilitates osteogenic
differentiation of human adiposed-derived stem cells in a co-culture system
[H5] The biosafety evaluation of culture-expanded human chondrocytes with
growth factor cocktail: a preclinical study
[H5] In situ normoxia enhances survival and proliferation rate of human
adipose tissue-derived stromal cells without increasing the risk of tumorigenesis
[H5] Pro-angiogenic potential of human chorion-derived stem cells in vitro and in vivo evaluation
[H5] Endogenous and induced angiogenic characteristics of human chorion-derived stem cells
[H5] Comparative profiling of stemness markers expressed by human umbilical vein endothelial cells and
human umbilical cord matrix-derived stem cells
[H5] Human adipose-derived mesenchymal stem cells promote recovery of injured
HepG2 cell line and show sign of early hepatogenic differentiation
[H5] Polycaprolactone-based scaffolds facilitates osteogenic differentiation
of human adiposed-derived stem cells in a co-culture system
[H5] Mission
[H5] Philosophy
[H5] Commitment
[H5] • Surveillance contained in the guidance document and guidelines for the registration of CGTP in Malaysia and PIC/s, Good Manufacturing Practice Guidelines and Annexes for Pharmaceuticals APB
[H5] • ISO/IEC 17025 Testing and Calibration Laboratories on Mesenchymal Stromal Cell MSCs
i. Cell Count
ii. Cell Viability
• ISO 14644 Cleanrooms and Associated Controlled Environment
[H6] ISO/IEC 17025 Certified Biology and Mechanical Testing Services
[H6] Stem Cell Research and Applications
[H6] Mesenchymal Stem Cell (MSC) Research and Therapy
[H6] Natural Killer Cell (NK Cell) Immunotherapy
[H6] Exosome Research and Applications
[H6] MSC derived Exosome Research and Applications
[H6] Research and Developments Publications
[H6] Accredited International Standards & Certified Auditor
[H6] REGISTERED
[H6] About Us
[H6] About Supergenics
[H6] Investor
[H6] Contact Us
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Länge : 14
Favoriten Icon
supergenics.de stellt ein Favicon bereit. Dieses kleine Symbol verbessert Wiedererkennung in Browser-Tabs, Lesezeichen und Suchergebnisumgebungen.
Druckeigenschaften
Für supergenics.de wurden keine speziellen Druck-CSS-Angaben gefunden. Eigene Print-Styles können helfen, Navigation, Farben und Layout beim Drucken sinnvoll zu reduzieren.
Sprache
Die Spracheinstellung von supergenics.de ist vorhanden: en. Diese Angabe macht das Dokument für Crawler und assistive Technologien klarer interpretierbar.
Dublin Core
Bei supergenics.de wurden keine Dublin-Core-Elemente gefunden. Das ist nicht für jede Website zwingend, kann aber bei dokumentenartigen oder redaktionellen Inhalten nützlich sein.
Dokument
Sauberes HTML, eine korrekte Zeichencodierung und moderne Standards verbessern Kompatibilität, Zugänglichkeit und die zuverlässige Verarbeitung der Seite.
Doctype
HTML 5
Verschlüsselung
supergenics.de deklariert den Zeichensatz UTF-8. Das ist wichtig, damit Sonderzeichen, Umlaute und typografische Zeichen korrekt dargestellt werden.
W3C Validität
Fehler : 0
Warnungen : 0
E-Mail Datenschutz
supergenics.de sollte offen sichtbare E-Mail-Adressen absichern. Eine geschützte Darstellung verringert die Wahrscheinlichkeit automatisierter Spam-Erfassung. Mit diesem kostenlosen Werkzeug lassen sich Adressen besser schützen.
Veraltetes HTML
supergenics.de verwendet keine überholten HTML-Tags in den geprüften Inhalten. Das spricht für eine zeitgemäße technische Basis.
Tipps zur Webseitengeschwindigkeit
Bei supergenics.de wurden keine verschachtelten Tabellen erkannt. Das ist positiv für sauberes Markup und responsive Gestaltung.
Auf supergenics.de wurden Inline-CSS-Angaben gefunden. Wenn möglich, sollten diese Regeln in Stylesheets verlagert werden, damit Gestaltung und Inhalt sauberer getrennt sind.
supergenics.de bindet 17 CSS-Dateien ein und liegt damit über dem empfohlenen Richtwert von 8. Eine Zusammenfassung oder Bereinigung kann Anfragen reduzieren.
supergenics.de bindet mit 11 JavaScript-Dateien nur eine begrenzte Menge Skripte ein. Das ist eine gute Grundlage für schnelle Ladezeiten.
Gzip ist für supergenics.de aktiv. Komprimierte Antworten sparen Datenvolumen und beschleunigen die Auslieferung der Seite.
Mobile
Mobile Optimierung ist wichtig, weil viele Besucher Smartphones nutzen. Viewport, Icons und ungeeignete Technologien beeinflussen Darstellung und Bedienbarkeit.
Mobile Optimierung
Apple Icon
META Viewport Tag
Flash Inhalt
Optimierung
Sitemap, robots.txt, Komprimierung und Analysesysteme beeinflussen, wie effizient eine Website gecrawlt, ausgeliefert und gezielt weiterentwickelt werden kann.
XML-Sitemap
Fehlt
supergenics.de sollte eine XML-Sitemap bereitstellen. Gerade bei größeren oder häufig geänderten Projekten erleichtert sie die Erfassung durch Suchmaschinen.
Robots.txt
http://supergenics.de/robots.txt
Eine robots.txt ist für supergenics.de vorhanden. Das ist die richtige Stelle, um Suchmaschinen den Umgang mit bestimmten Bereichen der Website zu erklären.
Analytics
Fehlt
Für supergenics.de wurde kein Analyse-Tool erkannt. Ohne Webanalyse bleibt schwer nachvollziehbar, wie Besucher die Seite tatsächlich nutzen.
PageSpeed Insights
PageSpeed Insights bewertet Leistung, Barrierefreiheit, bewährte Verfahren und SEO für Desktop und Mobilgeräte und macht technische Bremsen sichtbar.
Gerät
Kategorien
Website-Überprüfung
Website-Überprüfung ist ein kostenloses SEO Werkzeug zur Analyse Ihrer Webseite